Projects 

1

Searching for the molecular bases of mephedrone-induced biphasic response to social interactions in rats

2020/37/N/NZ7/01564, The National Science Centre, Poland, PRELUDIUM 19, PI: Olga Wronikowska

2

The role of neuropeptide Y in noradrenergic modulation of recognition and procedural memory

The National Science Center, Poland, MINIATURA 4, PI: Agnieszka Michalak

3

Interdisciplinary view on activity of coumarins on the central nervous system - behavioral, analytical and mode of action studies 

2018-2021 NCN 2017/27/B/NZ4/00917. The National Science Centre, Poland, OPUS 14. PI: Krystyna Skalicka-Wóźniak.

4

Interdisciplinary approach to the role of the GABA-ergic and glutamatergic neurotransmission in the effects of mephedrone - behavioral, biochemical and ex vivo studies

2017-2020 NCN 2017/25/B/NZ7/02410. The National Science Centre, Poland, OPUS 13. PI: Barbara Budzyńska. 

5

Influence of the chemical structure of coumarins derivatives on their central effects evaluated in behavioral and biochemical studies

 2015-2017 - NCN 2014/13/B/NZ4/01249. The National Science Centre, Poland, OPUS 7. PI: Barbara Budzyńska.

6

Behavioral and biochemical evaluation of mephedrone's action and interaction with other psychoactive drugs

2014-2016 - NCN 2013/11/B/NZ7/04837. The National Science Centre, Poland OPUS 6. PI: Grażyna Biała, Principal Investigator: Barbara Budzyńska.

7

               The study of structural and functional mechanisms of action of nicotinic receptors modulators

2014-2016 NCN 2013/09/D/NZ7/04549. The National Science Centre, Poland SONATA 5. PI: Katarzyna Targowska-Duda. Investigator: Barbara Budzyńska

Articles:

Kozioł E, Deniz FSS, Orhan IE, Marcourt L, Budzyńska B, Wolfender JL, Crawford AD, Skalicka-Woźniak K. High-performance counter-current chromatography isolation and initial neuroactivity characterization of furanocoumarin derivatives from Peucedanum alsaticum L (Apiaceae). Phytomedicine. 2019 Feb 15;54:259-264. doi: 10.1016/j.phymed.2018.10.030.

Boguszewska-Czubara A, Kurzepa J, Biała G, Kaszubska K, Grot K, Tarkowski P, Kowalczyk J, Silvestro S, Faggio C, Budzyńska B. Mephedrone Impact on Matrix Metalloproteinases Activity - Do they Influence the Memory Processes? Curr Mol Pharmacol. 2019;12(2):115-121. doi: 10.2174/1874467212666190114154307.

Targowska-Duda K, Budzynska B, Michalak A, Jozwiak K, Biala G, Arias HR. 3-Furan-2-yl-N-p-tolyl-acrylamide, a highly selective positive allosteric modulator of α7 nicotinic receptors, produces anxiolytic-like activity in mice. J Psychopharmacol. 2019 May;33(5):558-567. doi: 10.1177/0269881118821100.

Boguszewska-Czubara A, Budzynska B, Skalicka-Wozniak K, Kurzepa J. Perspectives and new aspects of metalloproteinases' inhibitors in therapy of CNS disorders: from chemistry to medicine. Curr Med Chem. 2018 May 13. doi: 10.2174/0929867325666180514111500.

Skalicka-Wozniak K, Budzynska B, Biala G, Boguszewska-Czubara A. Scopolamine-Induced Memory Impairment Is Alleviated by Xanthotoxin: Role of Acetylcholinesterase and Oxidative Stress Processes. ACS Chem Neurosci. 2018 May 16;9(5):1184-1194. doi: 10.1021/acschemneuro.8b00011.

Biala G, Pekala K, Boguszewska-Czubara A, Michalak A, Kruk-Slomka M, Grot K, Budzynska B. Behavioral and Biochemical Impact of Chronic Unpredictable Mild Stress on the Acquisition of Nicotine Conditioned Place Preference in Rats. Mol Neurobiol. 2018 Apr;55(4):3270-3289. doi: 10.1007/s12035-017-0585-4.

Budzynska B, Skalicka-Wozniak K, Kruk-Slomka M, Wydrzynska-Kuzma M, Biala G. In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone. Psychopharmacology (Berl). 2016 Jun;233(12):2289-300. doi: 10.1007/s00213-016-4279-9.

Biala G, Pekala K, Boguszewska-Czubara A, Michalak A, Kruk-Slomka M, Budzynska B. Behavioral and Biochemical Interaction Between Nicotine and Chronic Unpredictable Mild Stress in Mice. Mol Neurobiol. 2017 Mar;54(2):904-921. doi: 10.1007/s12035-016-9701-0.

Skalicka-Woźniak K, Orhan IE, Cordell GA, Nabavi SM, Budzyńska B. Implication of coumarins towards central nervous system disorders. Pharmacol Res. 2016 Jan;103:188-203. doi: 10.1016/j.phrs.2015.11.023

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